35 articles - From Friday Jul 11 2025 to Friday Jul 18 2025
Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…
| J Crohns Colitis |
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| Pancreatology |
International Association of Pancreatology Revised Guidelines on Acute Pancreatitis 2025. The recommendations presented here should serve as an evidence-based resource for practicing physicians and caregivers to treat patients with AP more effectively. In addition, the guidelines identify areas for future research, mainly targeted therapies for controlling systemic inflammation and mitigating organ dysfunction. |
meta-analyses and systematic reviews
| J Crohns Colitis |
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A Network Meta-analysis of Capsule Endoscopy Versus Imaging Modalities for Diagnosing Small Bowel Crohn's Disease. VCE exhibited superior diagnostic performance for detecting established proximal SB-CD compared to other imaging modalities. Clinicians should weigh the benefits and risks, and incorporate other modalities, such as MRE and IUS to optimize diagnosis and management. |
Scoring indices for assessing endoscopic disease activity in acute severe ulcerative colitis: A systematic review. These results highlight the need for a validated endoscopic score that can accurately describe and quantify the severity of endoscopic lesions and potentially predict outcomes in ASUC patients. |
| Liver Transpl |
Survivorship interventions after liver transplantation (LT): A systematic review of interventions targeting physical and psychosocial wellbeing after LT. There is limited data on promoting post-LT education, as well as social work and caregiver interventions. Future research should consider these areas for study; high quality interventions need to incorporate stakeholder input, target later LT survivorship stages, and apply consistent definitions of patient-centered outcomes using validated measures. |
RCT, clinical trials, retrospective studies, etc…
| Am J Clin Nutr |
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Association between habitual adherence to the planetary-health diet and mortality and major chronic disease risk among UK Biobank participants. Our results point towards an inverse association between habitual adherence to the PHD and all-cause mortality and cancer risk, although the associations with cancer depended on the cancer type. Our study provides additional evidence that sustainable diets can improve human health. |
Dietary diversity as a modifier of the effect of supplementation with multiple micronutrients during pregnancy on low birth weight in a randomized controlled trial in Bangladesh. In rural Bangladesh, where maternal dietary diversity was generally low, MMS (compared to IFA) supplementation had the strongest effect on reducing low birth weight among pregnant females with the least diverse diet, possibly reflecting the additional benefit of supplementation in this vulnerable group. Clinicaltrials Gov identifier NCT00860470. |
Heterogeneity in the association between a dietary pattern high in fat, sugar, and sodium and adverse pregnancy outcomes by maternal characteristics: a US pregnancy cohort study. This work may provide clues that contribute to a deeper understanding of the heterogeneity in dietary responses in pregnancy. |
The Value of an Ecological Approach to Address Micronutrient Malnutrition. We present a conceptual framework for applying this ecological perspective with foci on: 1) How to apply this approach to assessments that capture the complexity of the nutritional ecology; and 2) How to expand he understanding of the biology of MNs in biological systems and the environmental factors that influence them. Suggestions are included for a targeted clinical, public health and research agenda to inform the development of context-specific, nutritional assessment and interventions. |
| Inflamm Bowel Dis |
Endoscopic Recurrence in Crohn's Disease Patients With Long-Term Ileostomy. In this retrospective study, 77.3% of ileostomy patients underwent endoscopic assessment during follow-up. Ileal recurrence was detected in 39.7% of patients who underwent endoscopic evaluation. Patients with ileal involvement or preoperative exposure to biologics had the highest risk of recurrence. These patients might benefit from endoscopic monitoring. Fecal calprotectin is a reliable noninvasive marker for detecting ileal inflammation. |
Group-Delivered Mindfulness-Based Cognitive Therapy to Reduce Psychological Distress and Improve Sleep in Patients With Inflammatory Bowel Diseases: A Multicenter Randomized Controlled Trial (MindIBD). Mindfulness-Based Cognitive Therapy can be considered a valuable addition to the limited effective psychosocial interventions set for IBD patients, as it reduces psychological distress and improves well-being. This study also shows the possible impact of MBCT on biological processes, such as sleep and inflammation. |
Isolated Anastomotic Ulcers Are Associated with a Higher Long-Term Risk for Postoperative Recurrence and a Differential Mucosa-Associated Microbiome Composition in Patients with Crohn's Disease Following Ileocolic Resection. IAUs in CD patients with otherwise healthy neo-TI at first postoperative ileocolonoscopy are associated with long-term POR. In addition, a differential mucosa-associated microbiome composition was observed in patients with IAUs, specifically the proteobacteria Klebsiella, suggesting that putative taxa are related to these lesions. Further validation studies in larger cohorts, along with mechanistic studies, are still required. |
| J Crohns Colitis |
Clonal hematopoiesis of indeterminate potential and risk of incident Crohn's disease-a prospective cohort study. CHIP was associated with a markedly increased risk of subsequent CD. The association was particularly stronger in JAK2-mutant CHIP, ASXL1-mutant CHIP, and DNMT3A-mutant CHIP. The findings of this study may offer potential insights for future investigations into the mechanistic underpinnings of CD. |
Mirikizumab impact on disease clearance in patients with moderately to severely active ulcerative colitis: analysis of a pre-specified LUCENT trial endpoint. Mirikizumab consistently demonstrated disease clearance across induction, maintenance, and long-term studies. The attainment of disease clearance was associated with greater improvement in PROs, and early achievement of disease clearance was associated with better long-term outcomes, including clinical remission, corticosteroid-free remission, endoscopic and histological outcomes, reduced stool frequency, and rectal bleeding. |
| Liver Transpl |
Geographic variation in utilization of deceased donor livers in the United States in the era of advanced perfusion. On adjusted analysis, candidates in LUCs had lower likelihood of transplant (HR=0.88, p <0.001) but also lower waitlist mortality (HR=0.95, p <0.001). The advent of advanced perfusion was associated with utilization of otherwise marginal liver allografts and ameliorating geographic imbalances in discard seen with successive allocation policy eras. |
Machine learning improves post-transplantation hepatocellular carcinoma recurrence prediction. We developed a novel ML model that outperforms a widely used post-transplantation HCC recurrence risk score. This model may be used to better risk stratify patients following transplantation and tailor surveillance/adjuvant therapy. The pre-transplantation ML model may be used with the Milan Criteria to further risk stratify patients being considered for transplantation. |
Risk factors for in-hospital postoperative complications and 6-month graft survival after liver transplantation: A multicenter cohort study. In conclusion, postoperative complications, such as graft dysfunction, AKI and severe complications, were frequent after LT. We identified risk factors, such as donor and graft characteristics, MELD 3.0 and preoperative requirement for organ support, that may inform transplant risk evaluation. |
Steatotic liver disease is the dominant indication for liver transplantation in both europe and the United States: Trends and outcomes in the past two decades. (all p 1.0, p<0.01), similar between ELTR and SRTR, in patients without and with HCC. ALD and NASH/MASH are now leading indications for liver transplantation in two large global regions. |
The cirrhosis-hospital frailty risk score predicts mortality in patients with chronic liver disease: Analysis of a nationally representative database. Among patients with cirrhosis, the cHFRS demonstrated superior prediction of in-hospital mortality, compared to the original HFRS score. These findings support the use of cHFRS rather than HFRS as a comorbidity index in future studies of cirrhosis patients utilizing administrative data. |
| Pancreatology |
Associations between MRI and endoscopic ultrasound findings in the pancreas in children and young adults with suspected chronic pancreatitis. MRI findings related to the pancreatic duct and of parenchymal atrophy were moderately associated with EUS Rosemont Criteria classification. Correlations between individual EUS and MRI findings generally ranged from weak to moderate and were highest (coefficient ≤ 0.63) for main duct findings. |
Pediatric pancreas segmentation from MRI scans with deep learning. PanSegNet represents the first validated deep learning solution for pancreatic MRI segmentation, achieving expert-level performance across healthy and diseased states. This tool, algorithm, along with our annotated dataset, are freely available on GitHub and OSF, advancing accessible, radiation-free pediatric pancreatic imaging and fostering collaborative research in this underserved domain. |
Plenty of the editorials are available as full text through the publisher website using the provided link
| Inflamm Bowel Dis |
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| J Crohns Colitis |
misc publications eg case reports, tools of the trade, images of the month, etc…
| Inflamm Bowel Dis |
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| Liver Transpl |
| Pancreas |
Letters to the editors and authors’ replies
| Pancreatology |
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